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SML2348

BAY-707

≥98% (HPLC)

Promotion Available

Synonym(s):

(S)-N-Ethyl-4-(3-methylmorpholino)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
2 920,00 CZK
2 482,00 CZK
25 mg
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11 200,00 CZK

About This Item

Empirical Formula (Hill Notation):
C15H20N4O2
CAS Number:
Molecular Weight:
288.34
UNSPSC Code:
12352200
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder

2 482,00 CZK

List Price2 920,00 CZKSave 15%
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(NCC)C1=CC2=C(N1)N=CC=C2N3CCOC[C@@H]3C

InChI

1S/C15H20N4O2/c1-3-16-15(20)12-8-11-13(4-5-17-14(11)18-12)19-6-7-21-9-10(19)2/h4-5,8,10H,3,6-7,9H2,1-2H3,(H,16,20)(H,17,18)/t10-/m0/s1

InChI key

RPMGXDCRCWWCRY-JTQLQIEISA-N

Biochem/physiol Actions

BAY-707 is an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1), which hydrolyzes oxidized purine nucleoside triphosphates that might otherwise be incorporated into DNA/RNA and contribute to DNA damage. BAY-707 was shown to be a substrate-competitive, selective MTH1 inhibitor with an IC50 value of 2.3 nM.
Inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1)

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This Item
SML0651V5015SML1757
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: >50 mg/mL

solubility

DMSO: 10 mg/mL, clear

color

white to beige

color

white to beige

color

-

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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