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  • Effect of triterpenoid saponins from Bacopa monniera on scopolamine-induced memory impairment in mice.

Effect of triterpenoid saponins from Bacopa monniera on scopolamine-induced memory impairment in mice.

Planta medica (2009-02-14)
Yun Zhou, Ling Peng, Wei-Dong Zhang, De-Yun Kong
ANOTACE

Three new saponins, bacopasides IX-XI (1- 3), together with their known analogues bacopaside I (4), bacopaside II (5), bacopasaponsin C (6), and bacopasaponsin D (7), were isolated from the whole plant of Bacopa monniera. Compounds 3, 4, and 6 showed nootropic activity when tested in the Morris water maze test and step-down test of scopolamine-induced memory impairment in mice.

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Sigma-Aldrich
(±)-Huperzine A, synthetic, ≥98% (TLC)