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Merck

Ursolic acid: an anti-tumorigenic and chemopreventive activity. Minireview.

Neoplasma (2001-11-20)
L Novotný, A Vachálková, D Biggs
ANOTACE

Ursolic acid, UA, as a pentacyclic triterpene is of interest to scientists in the area of oncology because of its cytotoxicity, induction of differentiation, anti-mutagenic, antiviral and anti-invasive activities. UA is capable of inducing apoptosis in tumor cells on one side and to prevent malignant transformation of normal cells on the other side. It also interferes with numerous enzymes, including the ones serving directly to DNA synthesis. The aim of this review is to summarize reports on UA biological properties and to show its main anti-tumor effects and chemopreventive properties in normal cells.

MATERIÁLY
Číslo produktu
Značka
Popis produktu

Supelco
Ursolic acid, analytical standard
Sigma-Aldrich
Ursolic acid, ≥90%
Ursolic acid, primary reference standard
Ursolic acid, European Pharmacopoeia (EP) Reference Standard