U6628
Uvaol
≥95%
Synonyma:
Urs-12-ene-3,28-diol
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O této položce
Empirický vzorec (Hillův zápis):
C30H50O2
Číslo CAS:
Molekulová hmotnost:
442.72
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
208-888-3
MDL number:
Technický servis
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Dovolte nám, abychom vám pomohliQuality Segment
assay
≥95%
mp
223-225 °C (lit.)
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C
InChI
1S/C30H50O2/c1-19-10-15-30(18-31)17-16-28(6)21(25(30)20(19)2)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h8,19-20,22-25,31-32H,9-18H2,1-7H3/t19-,20+,22+,23-,24+,25+,27+,28-,29-,30-/m1/s1
InChI key
XUARCIYIVXVTAE-ZAPOICBTSA-N
Gene Information
mouse ... Nos2(18126)
General description
Uvaolis a pentacyclic triterpene compound usually extracted from plant leaves such as Apocynum venetum L., olive leaves (Olea europaea L.), and oregano (Origanum vulgare L.).
Application
Uvaol has been used as retinoic acid receptor-related orphan receptor gamma t (RORγt) inhibitor to study the role of cardiac glycoside reductase 2 (Cgr2) enzyme on its metabolism.
Biochem/physiol Actions
Uvaolexerts pharmacological properties such as antioxidant, anticancer, anti-inflammatory, and wound healing. It also displays vasodilator, hepatoprotective, and antimicrobial effects. Uvaol has inhibitory effects on nitric oxide (NO) release.
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Související obsah
Shi-Yun Du et al.
Chinese medicine, 15, 43-43 (2020-05-16)
Apocynum venetum leaves are used as a kind of phytomedicine and the main ingredient in some traditional Chinese medicine products for the relief of colitis. To understand the bioactive constituents of A. venetum L., we did a phytochemistry study and
Emad M Hassan et al.
Planta medica, 74(14), 1749-1750 (2008-11-01)
Phytochemical investigation of the methanolic extract of Plumeria acutifolia (Apocynaceae) leaves has led to the isolation and identification by spectroscopic means of a new monoterpene alkaloid, (R)-4'-((S)-1-hydroxyethyl)-5,6-dihydro-5' H-spiro[cyclopenta[C]pyridine-7,2'-furan)-5'-one, for which the name plumerianine was adopted, the iridoid 15-demethylplumeride, and three
B S Min et al.
Planta medica, 65(4), 374-375 (1999-06-12)
The methanol extracts of the leaves of Crataegus pinnatifida showed potent inhibitory activities against HIV-1 protease at a concentration of 100 micrograms/ml. The subsequent fractionation and isolation of the extract gave two active compounds. Their structures were identified as uvaol
Globální číslo obchodní položky
| Skladová položka | GTIN |
|---|---|
| U6628-25MG | 04061837409929 |