U6628

Uvaol

≥95%

• Synonyma: Urs-12-ene-3,28-diol
• Empirický vzorec (Hillův zápis): C₃₀H₅₀O₂
• Číslo CAS: 545-46-0
• Molekulová hmotnost: 442.72
• EC Number: 208-888-3
• MDL number: MFCD00009620
• UNSPSC Code: 12352103
• PubChem Substance ID: 24900437
• NACRES: NA.25

Vlastnosti

• assay: ≥95%
• mp: 223-225 °C (lit.)
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C
• InChI: 1S/C30H50O2/c1-19-10-15-30(18-31)17-16-28(6)21(25(30)20(19)2)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h8,19-20,22-25,31-32H,9-18H2,1-7H3/t19-,20+,22+,23-,24+,25+,27+,28-,29-,30-/m1/s1
• InChI key: XUARCIYIVXVTAE-ZAPOICBTSA-N
• Gene Information: mouse ... Nos2(18126)

Popis

General description

Uvaolis a pentacyclic triterpene compound usually extracted from plant leaves such as Apocynum venetum L., olive leaves (Olea europaea L.), and oregano (Origanum vulgare L.).

Application

Uvaol has been used as retinoic acid receptor-related orphan receptor gamma t (RORγt) inhibitor to study the role of cardiac glycoside reductase 2 (Cgr2) enzyme on its metabolism.

Biochem/physiol Actions

Uvaolexerts pharmacological properties such as antioxidant, anticancer, anti-inflammatory, and wound healing. It also displays vasodilator, hepatoprotective, and antimicrobial effects. Uvaol has inhibitory effects on nitric oxide (NO) release.

Bezpečnostní informace

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable