U3750

Uridine

≥99%, synthetic (organic), powder

• Synonyma: 1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
• Empirický vzorec (Hillův zápis): C₉H₁₂N₂O₆
• Číslo CAS: 58-96-8
• Molekulová hmotnost: 244.20
• NACRES: NA.51
• PubChem Substance ID: 24900640
• UNSPSC Code: 41106305
• EC Number: 200-407-5
• MDL number: MFCD00006526
• Beilstein/REAXYS Number: 754902
• Assay: ≥99%
• Biological source: synthetic (organic)
• Form: powder
• Solubility: H₂O: 50 mg/mL, clear, colorless

Vlastnosti

• Název produktu: Uridine, ≥99%
• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥99%
• form: powder
• mp: 163-167 °C (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless
• SMILES string: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
• InChI key: DRTQHJPVMGBUCF-XVFCMESISA-N
• Gene Information: mouse ... Uck1(22245)

Popis

General description

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

Application

Uridine has been used:

• as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
• in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
• in chase sequencing experiments

Biochem/physiol Actions

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)