The solvents recommended for this compound are as follows:
DMF: 2 mg/ml
DMSO: 3 mg/ml
Ethanol: 20 mg/ml
Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
SML1648
24(S)-Hydroxycholesterol
≥98% (HPLC), cholesterol metabolite, powder
Synonyma:
24S-Hydroxycholesterol, 5-Cholesten-3β,24(S)-diol, Cerebrosterin, Cerebrosterol, Cholest-5-ene-3β,24-diol
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
| Vám/Skladová položka | Dostupnost | Cena |
|---|---|---|
1 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 3 180,00 Kč |
5 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 13 000,00 Kč 11 050,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C27H46O2
Číslo CAS:
Molekulová hmotnost:
402.65
UNSPSC Code:
12352211
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
3 180,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohliNázev produktu
24(S)-Hydroxycholesterol, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -45 to -52°, c = 1 in chloroform-d
storage condition
desiccated
color
white to beige
solubility
DMSO: 3 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CC[C@H](O)C(C)C)C)(CC3)C)CC=C2C1)C
InChI
1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
InChI key
IOWMKBFJCNLRTC-XWXSNNQWSA-N
Biochem/physiol Actions
24(S)-Hydroxycholesterol is the major brain metabolite formed from cholesterol in the brain and is important for brain cholesterol homeostasis in addition to being an an endogenous agonist of the nuclear liver X receptors (LXRs).
24(S)-Hydroxycholesterol is the major brain metabolite formed from cholesterol in the brain and is important for brain cholesterol homeostasis in addition to being an an endogenous agonist of the nuclear liver X receptors (LXRs). Impairment of brain cholesterol metabolism has been associated with several neurodegenerative diseases, including multiple sclerosis, Alzheimer′s, and Huntington diseases. The exact role role of 24(S)-Hydroxycholesterol is unclear, and it may have differing effects depending on concentration. Low concentrations can protect neuronal cells against oxidative stress, while high concentrations induce necroptosis-like neuronal cell death. 24(S)-Hydroxycholesterol has also been found to be a potent allosteric modulator of N-methyl-d-aspartate receptors, potentiating NMDAR-mediated EPSCs in rat hippocampal neurons with an EC50 of 1.2 μM.
1 of 1
Tato položka | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (TLC) | assay ≥98% |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level - | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. room temp | storage temp. room temp |
| solubility DMSO: 3 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear (warmed) | solubility - | solubility - |
| storage condition desiccated | storage condition - | storage condition - | storage condition - |
Still not finding the right product?
Explore all of our products under 24(S)-Hydroxycholesterol
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Vyberte jednu z posledních verzí:
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
-
How the powder should be resuspended?
1 answer-
Helpful?
-