S6626

Strophanthidin

cardiotonic steroid

• Synonyma: 3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Apocymarin, Convallatoxigenin, Corchorin, Corchoside A aglycone, Corchsularin, Cymarigenen, Erysimupicrone, K-Strophanthidin
• Empirický vzorec (Hillův zápis): C₂₃H₃₂O₆
• Číslo CAS: 66-28-4
• Molekulová hmotnost: 404.50
• NACRES: NA.77
• PubChem Substance ID: 24899714
• UNSPSC Code: 12352200
• EC Number: 200-626-6
• MDL number: MFCD00046266

Vlastnosti

• Název produktu: Strophanthidin,
• Quality Segment: 100
• storage temp.: −20°C
• SMILES string: C[C@@]12[C@@](CC[C@@H]2C(CO3)=CC3=O)(O)[C@]4([H])CC[C@]5(O)C[C@@H](O)CC[C@]5(C([H])=O)[C@@]4([H])CC1
• InChI: 1S/C23H32O6/c1-20-6-3-17-18(4-8-22(27)11-15(25)2-7-21(17,22)13-24)23(20,28)9-5-16(20)14-10-19(26)29-12-14/h10,13,15-18,25,27-28H,2-9,11-12H2,1H3
• InChI key: ODJLBQGVINUMMR-UHFFFAOYSA-N

Popis

Application

Strophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.³

Biochem/physiol Actions

Strophanthidin is a cardiotonic steroid that elevates the activity of Na⁺/K⁺-ATPase in cardiac myocytes.¹ It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.²

Bezpečnostní informace

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral
• Skladovací třída: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges