QC testing of the product utilizes the solvents Pyridine and Methanol. Rutin is reported to be soluble in DMSO at approximately 25 mg/ml. Solvents should be purged with an inert gas before use. No data is available concerning the product's cell toxicity.
R5143
Rutin hydrate
≥94% (HPLC), powder
Synonyma:
Quercetin-3-rutinoside hydrate, Vitamin P hydrate
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Vybrat velikost
Změnit zobrazení
| Vám/SKU | Dostupnost | Cena |
|---|---|---|
50 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 4 130,00 Kč |
100 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 7 410,00 Kč |
500 g | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 23 900,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C27H30O16 · xH2O
Číslo CAS:
Molekulová hmotnost:
610.52 (anhydrous basis)
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-814-1
Beilstein/REAXYS Number:
75455
MDL number:
4 130,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
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Dovolte nám, abychom vám pomohliQuality Segment
assay
≥94% (HPLC)
form
powder
color
yellow to green
mp
195 °C (dec.) (lit.)
solubility
pyridine: 50 mg/mL, DMSO: soluble, aqueous base: soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
[H]O[H].O[C@H]1[C@H](OC[C@H]([C@H]2O)O[C@@H](OC(C3=O)=C(C4=CC=C(O)C(O)=C4)OC5=C3C(O)=CC(O)=C5)[C@H](O)[C@H]2O)O[C@H]([C@@H]([C@H]1O)O)C
InChI
1S/C27H30O16.H2O/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9;/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3;1H2/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-;/m0./s1
InChI key
PGHSKTKIQIBATG-ZAAWVBGYSA-N
General description
Rutin hydrate has radioprotective and antiplatelet activity. Rutin reduces hepatic and blood cholesterol levels.
Application
Biochem/physiol Actions
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodiumethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
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Tato položka | |||
|---|---|---|---|
| description ≥94% (HPLC), powder | description analytical standard | description primary reference standard | description ≥99.9% trace metals basis |
| assay ≥94% (HPLC) | assay ≥94.0% (HPLC) | assay - | assay ≥99.9% trace metals basis |
| form powder | form - | form - | form powder |
| Quality Level 200 | Quality Level 100 | Quality Level - | Quality Level 100 |
| application(s) metabolomics | application(s) food and beverages | application(s) - | application(s) PEM fuel cells |
| solubility pyridine: 50 mg/mL, DMSO: soluble, aqueous base: soluble | solubility - | solubility - | solubility ethanol: soluble, water: soluble, acetone: soluble ((lit.)) |
| mp 195 °C (dec.) (lit.) | mp - | mp - | mp - |
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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In what amount of DMSO does rutin completely dissolve and is it not toxic to cells?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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