P9528

Polyuridylic acid potassium salt

• Synonyma: Poly(U) potassium salt
• Číslo CAS: 27416-86-0
• UNSPSC Code: 41106305
• NACRES: NA.51
• MDL number: MFCD00148052
• Assay: ≥98% (TLC)
• Form: lyophilized powder
• Solubility: water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
• Storage temp.: −20°C

Vlastnosti

• assay: ≥98% (TLC)
• Quality Segment: 200
• form: lyophilized powder
• solubility: water: 19.60-20.40 mg/mL, clear to slightly hazy, colorless
• storage temp.: −20°C
• SMILES string: [P](=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2[c]([nH][c](cc2)=O)=O)(O)O
• InChI: 1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
• InChI key: DJJCXFVJDGTHFX-XVFCMESISA-N

Popis

Application

Polyuridylic acid (Poly(U)), a homopolymer of uridine, is used as a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.

Preparation Note

Prepared from UDP using polynucleotide phosphorylase.

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable