Přejít k obsahu
Merck
Všechny fotografie(2)

Key Documents

View All Documentation

P4497

Sigma-Aldrich

Anti-Potassium Channel Kv1.3 (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonyma:

Anti-Voltage-gated Potassium Channel KV1.3

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
Všechny fotografie(2)

About This Item

MDL number:
MFCD02097210
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human, rat

technique(s)

flow cytometry: 0.5-5 μg
western blot: 1:200-1:500 using rat brain membranes and human Jurkat T lymphocytes.

UniProt accession no.

P22001

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

Související kategorie

Immunogen

synthetic peptide corresponding to amino acid residues 211-224 of human KV1.3. The sequence has 12/14 residues identical in rat and mouse.

Physical form

Lyophilized from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ještě jste nenalezli správný produkt?  

Vyzkoušejte náš produkt Nástroj pro výběr produktů.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

Již tento produkt vlastníte?

Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.

Navštívit knihovnu dokumentů

Joseph Andronic et al.
Biochimica et biophysica acta, 1828(2), 699-707 (2012-10-09)
Many functions of T lymphocytes are closely related to cell volume homeostasis and regulation, which utilize a complex network of membrane channels for anions and cations. Among the various potassium channels, the voltage-gated K(V)1.3 is well known to contribute greatly
Andreas Schulte-Mecklenbeck et al.
European journal of immunology, 45(9), 2602-2614 (2015-07-04)
Natural killer (NK) cells are a subset of cytotoxic lymphocytes that recognize and kill tumor- and virus-infected cells without prior stimulation. Killing of target cells is a multistep process including adhesion to target cells, formation of an immunological synapse, and
Weiwei Li et al.
Cancers, 14(11) (2022-06-11)
Pancreas ductal adenocarcinoma (PDAC) is one the most aggressive cancers and associated with very high mortality, requiring the development of novel treatments. The mitochondrial voltage-gated potassium channel, Kv1.3 is emerging as an attractive oncologic target but its function in PDAC
Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

Obraťte se na technický servis.