G7504

Guanosine 3′,5′-cyclic monophosphate

≥98% (HPLC), powder, intracellular mediator

• Synonyma: cGMP, cyclic GMP
• Empirický vzorec (Hillův zápis): C₁₀H₁₂N₅O₇P
• Číslo CAS: 7665-99-8
• Molekulová hmotnost: 345.21
• NACRES: NA.77
• PubChem Substance ID: 24895309
• UNSPSC Code: 41106305
• EC Number: 231-641-6
• MDL number: MFCD00070129
• Assay: ≥98% (HPLC)
• Form: powder

Vlastnosti

• Název produktu: Guanosine 3′,5′-cyclic monophosphate, ≥98% (HPLC), powder
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: white
• solubility: 0.2 M NaHCO₃: 50 mg/mL
• storage temp.: −20°C
• SMILES string: NC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1
• InChI: 1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)
• InChI key: ZOOGRGPOEVQQDX-UHFFFAOYSA-N

Popis

Biochem/physiol Actions

A major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides.

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

Features and Benefits

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves