B6032

BIS-TRIS hydrochloride

≥99.0% (titration)

• Synonyma: 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane
• Empirický vzorec (Hillův zápis): C₈H₁₉NO₅ · HCl
• Číslo CAS: 124763-51-5
• Molekulová hmotnost: 245.70
• MDL number: MFCD00171252
• UNSPSC Code: 12161700
• PubChem Substance ID: 24891891
• NACRES: NA.25

Vlastnosti

• Quality Level: 200
• assay: ≥99.0% (titration)
• form: crystalline powder
• useful pH range: 5.8-7.2
• pKa: 6.5
• solubility: water: 0.5 g/mL, clear, colorless to very faintly yellow
• application(s): diagnostic assay manufacturing
• storage temp.: room temp
• SMILES string: Cl.OCCN(CCO)C(CO)(CO)CO
• InChI: 1S/C8H19NO5.ClH/c10-3-1-9(2-4-11)8(5-12,6-13)7-14;/h10-14H,1-7H2;1H
• InChI key: VEYRVLHAMHQVTC-UHFFFAOYSA-N

Popis

Application

• Phos-tag SDS-PAGE systems for phosphorylation profiling of proteins with a wide range of molecular masses under neutral pH conditions.: This research introduces the use of BIS-TRIS hydrochloride in Phos-tag SDS-PAGE systems to profile protein phosphorylation. The system operates under neutral pH conditions, making it suitable for analyzing proteins with diverse molecular weights. This method enhances the resolution of phosphorylated proteins, facilitating detailed phosphorylation studies crucial for understanding cellular signaling and protein function (Kinoshita et al., 2012).

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable