65969
4-O-Caffeoylquinic acid
≥98.0%
Synonyma:
4-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid, Cryptochlorogenic acid
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O této položce
Empirický vzorec (Hillův zápis):
C16H18O9
Číslo CAS:
Molekulová hmotnost:
354.31
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Technický servis
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assay
≥98.0%
form
powder or crystals
optical activity
[α]/D -76.0±5.0°, c = 0.5 in H2O
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1OC(=O)\C=C\c2ccc(O)c(O)c2)C(O)=O
InChI
1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(21)25-14-11(19)6-16(24,15(22)23)7-12(14)20/h1-5,11-12,14,17-20,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1
InChI key
GYFFKZTYYAFCTR-JUHZACGLSA-N
General description
It is an ester of caffeic acid and quinic acid.
4-caffeoylquinic acid (4-CQA) is the derivative of caffeic acid (CA).
Application
4-O-Caffeoylquinic acid has been used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).
Biochem/physiol Actions
4-O-Caffeoylquinic acid (4-CQA) is a major active antioxidant marker in mulberry leaf extract. It is an inhibitor of ferroptosis hence, it is recognized as a potent anti-diabetic agent. 4-CQA plays an important role in the upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Skladovací třída
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
Gary R Takeoka et al.
Journal of agricultural and food chemistry, 51(2), 496-501 (2003-01-09)
Almond hulls (Nonpareil variety) were extracted with methanol and analyzed by reversed phase HPLC with diode array detection. The extract contained 5-O-caffeoylquinic acid (chlorogenic acid), 4-O-caffeoylquinic acid (cryptochlorogenic acid), and 3-O-caffeoylquinic acid (neochlorogenic acid) in the ratio 79.5:14.8:5.7. The chlorogenic
Bioactive Phenolics of the Genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS/MS Profile of the Siberian Species and Their Inhibitory Potential Against alpha-Amylase and alpha-Glucosidase
Olennikov D N, et al.
Frontiers in Pharmacology, 9 (2018)
Yi Zhou
Diabetes, metabolic syndrome and obesity : targets and therapy, 13, 1921-1931 (2020-07-02)
Mulberry leaf extract has exerted better antidiabetic activities, while the effects of major active components in mulberry leaf extract are still unclear. Cryptochlorogenic acid (CCA) as the major active component in mulberry leaf extracts was investigated herein. Rats were treated
Globální číslo obchodní položky
| Skladová položka | GTIN |
|---|---|
| 65969-10MG | 04061832733821 |
| 65969-50MG | 04061832404844 |