Y0000545

Thioctic acid containing impurity B

European Pharmacopoeia (EP) Reference Standard

• Synonyma: (±)-α-Lipoic acid, (±)-1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL-α-Lipoic acid, DL-6,8-Thioctic acid, Lip(S₂)
• Empirický vzorec (Hillův zápis): C₈H₁₄O₂S₂
• Číslo CAS: 1077-28-7
• Molekulová hmotnost: 206.33
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329831009
• MDL number: MFCD00005474
• Beilstein/REAXYS Number: 81853
• eCl@ss: 25140904

Vlastnosti

• grade: pharmaceutical primary standard
• API family: thioctic acid
• manufacturer/tradename: EDQM
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(=O)CCCCC1CCSS1
• InChI: 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
• InChI key: AGBQKNBQESQNJD-UHFFFAOYSA-N

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Thioctic acid containing impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Antioxidant and coenzyme needed for the activity of enzyme complexes such as pyruvate dehydrogenase and glycine decarboxylase.

Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• Piktogramy: GHS07,GHS09
• Výstražné slovo: Warning
• Kódy nebezpečí: H302,H315,H317,H319,H411
• Bezpečnostní pokyny: P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 2
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable