SYNPLE-H090

Reagent-cartridge 9-OMe-Benzoxazepane

Synple

• Synonyma: Synple 2
• UNSPSC Code: 12161503
• NACRES: NA.22
• MDL number: MFCD32903606

Vlastnosti

• Quality Segment: 100
• reaction suitability: reaction type: Heterocycle Formation
• parameter: up to 0.5 mmol scale
• SMILES string: [s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
• InChI: 1S/C28H38N4O7S/c1-17-24(40-16-30-17)19-7-5-18(6-8-19)14-29-26(37)21-13-20(33)15-32(21)27(38)25(28(2,3)4)31-22(34)9-11-39-12-10-23(35)36/h5-8,16,20-21,25,33H,9-15H2,1-4H3,(H,29,37)(H,31,34)(H,35,36)/t20-,21+,25-/m1/s1
• InChI key: HVPZHRHEHKZOOJ-TYBLODHISA-N

Popis

General description

Reagent-cartridge 9-OMe-Benzoxazepane is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the synthesis of a methoxy-substituted benzoxazepane heterocycle from an aldehyde through the use of a SnAP reagent. The cartridge contains all necessary reagents for transforming the chosen aldehyde into a methoxy-substituted benzoxazepane heterocycle.

Scale: up to 0.5 mmol
Heterocycle: Methoxy-substituted benzoxazepane
Compatible substrates: aldehyde

Cartridge contents:

• Immobilized SnAP reagent
• Cu catalyst (Cu(OTF)₂ and 2,6-lutidinium triflate)
• SCX (for purification)
• Silica (for purification)

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Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
• Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety - all chemicals are contained in the system, minimizing the user′s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system - simple installation
• Reaction temperatures from 25 °C - 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

For more information on heterocycle formation using SnAP reagents, visit here: SnAP Technology Spotlight

Legal Information

Product of Synple Chem AG

Bezpečnostní informace

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H411
• pcodes: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2
• Skladovací třída: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable