PHR1340

Pyrilamine maleate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: Pyrilamine maleate salt, Mepyramine maleate salt, N-(4-Methoxyphenyl)methyl-N′,N′-dimethyl-N-(2-pyridinyl)-1,2-ethanediamine maleate salt
• Empirický vzorec (Hillův zápis): C₁₇H₂₃N₃O · C₄H₄O₄
• Číslo CAS: 59-33-6
• Molekulová hmotnost: 401.46
• NACRES: NA.24
• PubChem Substance ID: 329823325
• UNSPSC Code: 41116107
• EC Number: 200-422-7
• MDL number: MFCD00069333

Vlastnosti

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to Ph. Eur. M0500000, traceable to USP 1588004
• API family: mepyramine, pyrilamine
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: OC(=O)\C=C/C(O)=O.COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
• InChI: 1S/C17H23N3O.C4H4O4/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15;5-3(6)1-2-4(7)8/h4-11H,12-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: JXYWFNAQESKDNC-BTJKTKAUSA-N
• Gene Information: human ... HRH1(3269)

Popis

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pyrilamine maleate is a first generation antihistamine drug, widely used to reduce all symptoms of cold and is also employed to reduce allergies both parenterally and locally.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Pyrilamine maleate may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique and liquid chromatography technique.

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA1092 in the slot below. This is an example certificate only and may not be the lot that you receive.

Bezpečnostní informace

• Piktogramy: GHS07
• Výstražné slovo: Warning
• Kódy nebezpečí: H302,H315,H319,H335
• Bezpečnostní pokyny: P261 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Cílové orgány: Respiratory system
• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 3
• Bod vzplanutí (°F): Not applicable
• Bod vzplanutí (°C): Not applicable