PHR1180

Imidazole

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyma: 1,3-Diaza-2,4-cyclopentadiene, Glyoxaline
• Lineární vzorec: C₃H₄N₂
• Číslo CAS: 288-32-4
• Molekulová hmotnost: 68.08
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329823192
• EC Number: 206-019-2
• Beilstein/REAXYS Number: 103853
• MDL number: MFCD00005183
• eCl@ss: 25140904

Vlastnosti

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to Ph. Eur. I0086000, traceable to USP 1336500
• vapor pressure: <1 mmHg ( 20 °C)
• API family: imidazole
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• pKa (25 °C): 6.95
• bp: 256 °C (lit.)
• mp: 88-91 °C (lit.)
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: c1c[nH]cn1
• InChI: 1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
• InChI key: RAXXELZNTBOGNW-UHFFFAOYSA-N

Popis

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Imidazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).

Excellent for buffers in the range of pH 6.2-7.8

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC4011 in the slot below. This is an example certificate only and may not be the lot that you receive.

Bezpečnostní informace

• Piktogramy: GHS08,GHS05,GHS07
• Výstražné slovo: Danger
• Kódy nebezpečí: H302,H314,H360D
• Bezpečnostní pokyny: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C
• Skladovací třída: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co se děje?: WGK 2
• Bod vzplanutí (°F): 293.0 °F - closed cup
• Bod vzplanutí (°C): 145 °C - closed cup