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L0790000

Lovastatin

European Pharmacopoeia (EP) Reference Standard

Synonyma:

Mevinolin

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
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About This Item

Empirický vzorec (Hillův zápis):
C24H36O5
Číslo CAS:
75330-75-5
Molekulová hmotnost:
404.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lovastatin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI key

PCZOHLXUXFIOCF-BXMDZJJMSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lovastatin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Č. produktu
Popis
Stanovení ceny

1370600

Lovastatin, United States Pharmacopeia (USP) Reference Standard

1370611

Lovastatin Related Compound A, United States Pharmacopeia (USP) Reference Standard

Y0001136

Lovastatin for peak identification, European Pharmacopoeia (EP) Reference Standard

1370655

Lovastatin Impurity Identification Mixture, United States Pharmacopeia (USP) Reference Standard

1236833

Lovastatin Epimer Mixture, United States Pharmacopeia (USP) Reference Standard

1443216

Mevastatin, United States Pharmacopeia (USP) Reference Standard

PHR2240

Mevastatin/Lovastatin Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2278

Lovastatin Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2279

Lovastatin Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2277

Lovastatin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Osvědčení o analýze (COA)

Lot/Batch Number

Je nám líto, ale pro tento produkt momentálně nemáme COA k dispozici online.

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Navštívit knihovnu dokumentů

Chia-Hao Chen et al.
International journal of pharmaceutics, 444(1-2), 18-24 (2013-01-29)
Lovastatin, categorized as a class II compound according to the Biopharmaceutics Classification System, is mainly responsible for the blood cholesterol lowering effect of red yeast rice (RYR). The aim of this study was to compare the dissolution rate, physical state
Emily K Osterweil et al.
Neuron, 77(2), 243-250 (2013-01-29)
Many neuropsychiatric symptoms of fragile X syndrome (FXS) are believed to be a consequence of altered regulation of protein synthesis at synapses. We discovered that lovastatin, a drug that is widely prescribed for the treatment of high cholesterol, can correct
Patricia A Reis et al.
PLoS pathogens, 8(12), e1003099-e1003099 (2013-01-10)
Cerebral malaria (CM) is the most severe manifestation of Plasmodium falciparum infection in children and non-immune adults. Previous work has documented a persistent cognitive impairment in children who survive an episode of CM that is mimicked in animal models of
Kimberly A Hartwell et al.
Nature chemical biology, 9(12), 840-848 (2013-10-29)
Efforts to develop more effective therapies for acute leukemia may benefit from high-throughput screening systems that reflect the complex physiology of the disease, including leukemia stem cells (LSCs) and supportive interactions with the bone marrow microenvironment. The therapeutic targeting of
Giovanni Provenzano et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(40), 13281-13288 (2014-10-03)
Genome-wide association studies indicated the homeobox-containing transcription factor Engrailed-2 (En2) as a candidate gene for autism spectrum disorders (ASD). Accordingly, En2 knock-out (En2(-/-)) mice show anatomical and behavioral "ASD-like" features, including decreased sociability and learning deficits. The molecular pathways underlying
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