OP80
Anti-APC (Ab-7) Mouse mAb (CC-1)
Synonyma:
Anti-Adenomatus Polyposis Coli
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
O této položce
NACRES:
NA.45
UNSPSC Code:
12352203
Clone:
CC-1, monoclonal
Species reactivity:
human, mouse, rat
Application:
ICC, IF, IHC (f)
Citations:
8
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohlibiological source
mouse
Quality Level
clone
CC-1, monoclonal
form
liquid
contains
≤0.1% sodium azide
species reactivity
human, mouse, rat
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
technique(s)
immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry (frozen sections): suitable
dilution
(Free-floating SectionsParaffin Sections)
isotype
IgG2b
shipped in
wet ice
storage temp.
2-8°C
General description
Recognizes APC in oligodendrocytes and astrocytes.
- Antibody Target Gene Symbol: APC
- Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC
- Entrez Gene Name: adenomatous polyposis coli
- Hu Entrez ID: 324 (Related Antibodies: ST1150, OP62, OP47L, OP44)
- Mu Entrez ID: 11789
- RatEntrez ID: 24205
Immunogen
a recombinant protein consisting of amino acids 1-226 of APC
Application
Frozen Sections (5 µg/ml) Immunofluorescence (5 µg/ml) Paraffin Sections (5 µg/ml, heat pre-treament required) Immunocytochemistry (see application references) Free Floating Sections (see application references)
Well suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody′s staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
Well suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody′s staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
Packaging
Please refer to vial label for lot-specific concentration
Physical form
In 50 mM sodium phosphate buffer, 0.2% gelatin.
Analysis Note
Negative control: MOPC 21 cells
Positive control: Purkinje cells or cerebellum tissue
Positive control: Purkinje cells or cerebellum tissue
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling
Skladovací třída
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Osvědčení o analýze (COA)
Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
L K Su et al.
Science (New York, N.Y.), 262(5140), 1734-1737 (1993-12-10)
Mutations of APC appear to initiate sporadic and inherited forms of human colorectal cancer. Although these mutations have been well characterized, little is known about the function of the APC gene product. Two cellular proteins that associate with APC were
L K Su et al.
Cancer research, 53(12), 2728-2731 (1993-06-15)
Germline mutations of the APC gene are responsible for familial adenomatous polyposis, an autosomal dominant inherited predisposition to colorectal tumors. Mutation of the APC gene is also an early, if not initiating, event for sporadic colorectal tumorigenesis. In both cases
J Groden et al.
Cell, 66(3), 589-600 (1991-08-09)
DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes (DP1, SRP19, and DP2.5) located within a 100 kb region deleted in two of the patients. The intron-exon boundary sequences were defined for
K J Smith et al.
Cancer research, 54(14), 3672-3675 (1994-07-15)
The adenomatous polyposis coli protein (APC) is mutated in familial adenomatous polyposis patients as well as in sporadic colorectal tumors. In an attempt to further understand the function of APC, the subcellular localization of APC was examined. Wild-type and mutant
High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system
Bhat, R.V., et al.
The Journal of Neuroscience, 14, 3059-3071 (1994)
Globální číslo obchodní položky
| Skladová položka | GTIN |
|---|---|
| OP80-100UG | 04055977209662 |
Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..
Obraťte se na technický servis