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Merck

AB2200

Anti-PRG4 Antibody

from rabbit, purified by affinity chromatography

Synonyma:

Megakaryocyte-stimulating factor, Superficial zone proteoglycan, articular superficial zone protein, bG174L6.2 (MSF: megakaryocyte stimulating factor ), megakaryocyte stimulating factor, proteoglycan 4, proteoglycan 4, (megakaryocyte stimulating factor,

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O této položce

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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Název produktu

Anti-PRG4 Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human, rat, primate, horse

technique(s)

immunocytochemistry: suitable
western blot: suitable

NCBI accession no.

NM_001127708.1

UniProt accession no.

Q92954

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PRG4(10216)

General description

~37 kDa
PRG4, Proteoglycan 4, is a human gene and is found in synovial tissue, cartilage, and liver. Small amounts are found in the lung. Isoform 1 is found in the kidney, lung, liver, heart and brain. The other Isoforms, C & D, are widely expressed. PRG4 is a lubricating glycoprotein containing chondroitin sulfate and keratan sulfate glycosaminoglycans. It is responsible for boundary lubrication at the cartilage surface. A disease associated with PRG4 is Jacobs’s syndrome which is an autosomal recessive disorder.

Immunogen

Epitope: C-Teminus
KLH-conjugated followed by PRG4 corresponding to the C-terminal region

Analysis Note

Control
Mouse Brain lysates
Western Blotting

Application

Anti-PRG4 Antibody is an antibody against PRG4 for use in WB & IC.
Immunocytochemistry:
Confocal IF analysis of N1E-115 using anti-PRG4 (1:500) Rabbit pAB (Red). Actin filaments have been labeled with Alexa Fluor 488 -Phalloidin (Green). Nuclear is stained with DAPI (Blue).
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Biochem/physiol Actions

Cat. # AB2220 recognizes PRG4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Preparation Note

Stable for 1 year at 2-8ºC from date of receipt.

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Skladovací třída

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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