672112

Urokinase, Human Urine

• Synonyma: Urokinase, Human Urine, uPA
• Číslo CAS: 9039-53-6
• Číslo EC: 3.4.99.26 (BRENDA, IUBMB)
• UNSPSC Code: 12352202
• NACRES: NA.25
• MDL number: MFCD00132566
• eCl@ss: 32160410
• Specific activity: ≥100,000 units/mg protein

Vlastnosti

• description: Merck USA index - 14, 9887
• Quality Segment: 100
• form: lyophilized solid
• specific activity: ≥100,000 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• shipped in: dry ice
• storage temp.: −20°C

Popis

General description

Native urokinase from human urine. A thrombolytic agent that converts plasminogen to plasmin. A mixture of high molecular weight (54 kDa) and low molecular weight (33 kDa) urokinase.

Note: 1 unit = 1 CTA unit = 0.7 Ploug units. 1 KU = 1000 units.

Physical form

Lyophilized from 200 mM mannitol, 100 mM NaCl, 50 mM Tris-HCl, 0.1% PEG, pH 7.5.

Preparation Note

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

Prepared from urine of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitute in distilled H₂O

Other Notes

Bell, W.R. 1975. Semin. Thromb. Res.2, 1.
Johnson, A.J., et al. 1969. Thromb. Diath. Haemorrh. 21, 259.

One unit is defined as the amount of enzyme equal to an international standard tested by the fibrinolytic method of Johnson, et al.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Bezpečnostní informace

• pictograms: GHS08
• signalword: Danger
• hcodes: H334
• pcodes: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3