5.06382

MPTP Hydrochloride

≥98% (TLC), solid, dopaminergic neurotoxin, Calbiochem

• Synonyma: MPTP Hydrochloride, Dopaminergic neurotoxin, MPTP
• Empirický vzorec (Hillův zápis): C₁₂H₁₅N · xHCl
• Číslo CAS: 23007-85-4
• Molekulová hmotnost: 173.25 (free base basis)
• MDL number: MFCD00012790
• UNSPSC Code: 12352200
• NACRES: NA.77

Vlastnosti

• Název produktu: MPTP Hydrochloride,
• assay: ≥98% (TLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: water: 100 mg/mL
• storage temp.: 2-8°C
• SMILES string: [Cl-].[N+H]1(CCC(=CC1)c2ccccc2)C
• InChI: 1S/C12H15N.ClH/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-7H,8-10H2,1H3;1H
• InChI key: KOWJANGMTAZWDT-UHFFFAOYSA-N

Popis

General description

A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson′s disease models in primates.

Warning

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Langston, J. W., et al. 1985. Trends in Neurosci.8, 79.

Gabriel, T. L., et al. 1999. Nature Med.5, 1403.
Zhang, X., et al. 2010. J. Proteome Res.9, 1496.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Bezpečnostní informace

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 - H370
• pcodes: P260 - P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - STOT SE 1
• target_organs: Nervous system
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3