407271

Integrin α_Mβ₂ Ligand - CAS 307525-40-2 - Calbiochem

• Synonyma: Integrin α_Mβ₂ Ligand - CAS 307525-40-2 - Calbiochem
• Empirický vzorec (Hillův zápis): C₁₉H₁₅NOS₂
• Číslo CAS: 307525-40-2
• Molekulová hmotnost: 337.46
• UNSPSC Code: 12352200
• MDL number: MFCD20134199

Vlastnosti

• assay: ≥98% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: yellow
• solubility: DMSO: 15 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Popis

General description

A cell-permeable thioxothiazolidine compound that displays anti-inflammatory properties. Shown to increase cell adhesion and lowers leukemia cell migration in vitro and leukocyte recruitment in vivo and displays anti-inflammatory properties. Binds to and stabilizes integrin α_M I domain active conformation and enhances the ligands′ (pro-MMP-9 and fibrinogen) binding ability.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Binds to and stabilizes integrin αM I domain active conformation

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Other Notes

Bjorklund, M., et al. 2006. Biochemistry45, 2862.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Bezpečnostní informace

• Skladovací třída: 10-13 - German Storage Class 10 to 13