This product is a purified mouse monoclonal IgG1κ in solution containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. The stability of this product is warranted for 1 year from the date of shipment, when stored at 2-8°C. The long term stability of this product when stored at -20°C or -80°C has not been investigated and may or may not extend the product shelf life. In general, avoid repeated freeze/thaw cycles.
05-831-I
Anti-Beta (β)-Amyloid antibody
mouse monoclonal, 12F4
Synonyma:
Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
| Vám/Skladová položka | Dostupnost | Cena |
|---|---|---|
100 μL | Očekávané datum odeslání28. srpna 2026odAreál Kühne+Nagel spol. s r.o. | 11 100,00 Kč |
O této položce
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
12F4, monoclonal
Species reactivity:
human
Application:
ELISA, IHC
Citations:
8
11 100,00 Kč
Očekávané datum odeslání28. srpna 2026podrobné informace
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohliNázev produktu
Anti-Amyloid Beta (ABeta) x-42 Antibody, clone 12F4, clone 12F4, from mouse
biological source
mouse
Quality Segment
antibody form
purified antibody
antibody product type
primary antibodies
clone
12F4, monoclonal
species reactivity
human
technique(s)
ELISA: suitable, immunohistochemistry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... APP(351)
General description
4 kDa calculated
One of the most important and initial steps which causes loss of memory and cognition in Alzheimer’s Disease (AD) involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 amino acid peptides (Amyloid Beta) 1-40, 1-42 and 1-43). Polymerization of beta-amyloid and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition.
Immunogen
KLH-conjugated linear peptide corresponding to human Amyloid Beta (ABeta) x-42.
Application
Anti-Amyloid Beta (ABeta) x-42, clone 12F4 is an antibody targeting the Amyloid Beta (ABeta) x-42 protein, validated for use in IHC & ELISA.
Immunohistohemistry Analysis: A 1:500 dilution from a representative lot detected Amyloid Beta (ABeta) x-42 in human pons/midbrain tissue.
ELISA Analysis: A representative lot detected Amyloid Beta (ABeta) x-42, but demonstrates a loss of signal against Amyloid Beta (ABeta) x-42.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Amyloid Beta (ABeta) x-42, but demonstrated a loss of signal against x-40 and not x-43 in WB (Prof. J. Buxbaum, Mt. Sinai School of Medicine).
ELISA Analysis: A representative lot detected Amyloid Beta (ABeta) x-42, but demonstrates a loss of signal against Amyloid Beta (ABeta) x-42.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Amyloid Beta (ABeta) x-42, but demonstrated a loss of signal against x-40 and not x-43 in WB (Prof. J. Buxbaum, Mt. Sinai School of Medicine).
Biochem/physiol Actions
This antibody detects Amyloid Beta (ABeta) x-42, but does not cross react with Amyloid Beta (ABeta) x-40 or Amyloid Beta (Abeta) x-43.
Physical form
Format: Purified
Analysis Note
Control
Human Alzheimer′s brain tissue.
Human Alzheimer′s brain tissue.
Evaluated by Immunohistochemistry in human Alzheimer′s disease brain tissue.
Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Amyloid Beta (Abeta) x-42 in human Alzheimer′s disease brain tissue.
Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Amyloid Beta (Abeta) x-42 in human Alzheimer′s disease brain tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 05-831
1 of 1
Tato položka | |||
|---|---|---|---|
| description clone 12F4, from mouse | description clone 2.F2.19B4, from mouse | description clone 22C11, from mouse, ALEXA FLUOR™ 488 | description from rabbit, purified by affinity chromatography |
| clone 12F4, monoclonal | clone 2.F2.19B4, monoclonal | clone 22C11, monoclonal | clone polyclonal |
| species reactivity human | species reactivity human, mouse | species reactivity rat, pig | species reactivity human |
| biological source mouse | biological source mouse | biological source mouse | biological source rabbit |
| antibody form purified antibody | antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form affinity isolated antibody |
| Gene Information human ... APP(351) | Gene Information human ... APP(351) | Gene Information human ... APP(351) | Gene Information human ... APP(351) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
Still not finding the right product?
Explore all of our products under Anti-Amyloid Beta (ABeta) x-42 Antibody, clone 12F4
— nebo —
Vyzkoušejte náš nástroj Nástroj pro výběr produktů a zúžte své možnosti.
Skladovací třída
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Vyberte jednu z posledních verzí:
Již tento produkt vlastníte?
Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.
-
Can this antibody be aliquoted and frozen at -80 degrees Celsius for long term storage? There is no information on the components in the antibody (e.g gelatin) or long term storage conditions. Thanks
1 answer-
Helpful?
-