799041

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

PEG average M_n 5,000, PLGA average M_n 25,000, lactide:glycolide 50:50

• Synonyma: PEG-PLGA, PEG-b-PLGA
• Lineární vzorec: CH₃[C₂H₄O]_nO[(C₂H₂O₂)_x(C₃H₄O₂)_y]_mH
• NACRES: NA.23
• UNSPSC Code: 12162002

Vlastnosti

• form: powder
• Quality Segment: 100
• mol wt: PEG average M_n 5,000, PLGA average M_n 25,000
• composition: lactide:glycolide 50:50
• storage temp.: 2-8°C

Popis

Application

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Features and Benefits

• Good biocompatibility, low immunogenicity and good degradability.
• Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• Co se děje?: WGK 3