540072

(R)-(−)-Epichlorohydrin

99%

• Synonyma: (R)-(−)-2-(Chloromethyl)oxirane
• Empirický vzorec (Hillův zápis): C₃H₅ClO
• Číslo CAS: 51594-55-9
• Molekulová hmotnost: 92.52
• UNSPSC Code: 12352103
• NACRES: NA.22
• PubChem Substance ID: 24878437
• EC Number: 424-280-2
• Beilstein/REAXYS Number: 1420785
• MDL number: MFCD00077759
• Assay: 99%

Vlastnosti

• vapor density: 3.29 (vs air)
• Quality Segment: 100
• vapor pressure: 10 mmHg ( 16.6 °C)
• assay: 99%
• optical activity: [α]20/D −34°, c = 1 in methanol
• optical purity: ee: 98% (GLC)
• autoignition temp.: 772 °F
• expl. lim.: 21 %
• refractive index: n20/D 1.438 (lit.)
• bp: 114 °C (lit.)
• density: 1.180 g/mL at 20 °C (lit.)
• functional group: chloro, ether
• SMILES string: ClC[C@H]1CO1
• InChI: 1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2/t3-/m0/s1
• InChI key: BRLQWZUYTZBJKN-VKHMYHEASA-N

Popis

Application

Building block for the synthesis of a key intermediate in the synthesis of stable PGI₂ analogue UT-15.

Used in the synthesis of chiral morpholines and dioxanes via a Mitsunobu diol-cyclization. Chiral building block in the enantioselective synthesis of trans-2,4-disubstituted piperidines.

Legal Information

Manufactured under license by Sterling Pharma Solutions Limited, using Jacobsen HKR technology.

Bezpečnostní informace

• Piktogramy: GHS02,GHS06,GHS08,GHS05
• Výstražné slovo: Danger
• Kódy nebezpečí: H226,H301 + H311 + H331,H314,H317,H350
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1
• Skladovací třída: 3 - Flammable liquids
• Bod vzplanutí (°F): 89.6 °F - closed cup
• Bod vzplanutí (°C): 32 °C - closed cup
• PPE (osobní ochranné prostředky): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
• Bezpečnostní pokyny: P210 - P280 - P301 + P310 + P330 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338