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440744

Polycaprolactone

greener alternative

Ekologičtější alternativa

average Mn 80,000

Synonyma:

2-Oxepanone homopolymer, 6-Caprolactone polymer

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Vybrat velikost

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Vám/Skladová položkaDostupnostCena
5 g
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1 930,00 Kč
250 g
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6 960,00 Kč
500 g
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11 000,00 Kč
2.5 kg
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13 200,00 Kč

O této položce

Lineární vzorec:
(C6H10O2)n
UNSPSC Code:
12162002
NACRES:
NA.23

1 930,00 Kč


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form

pellets (~3 mm)

Quality Segment

mol wt

average Mn 80,000

greener alternative product characteristics

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

<0.5% water

color

white to off-white

mp

60 °C (lit.)

density

1.145 g/mL at 25 °C

Mw/Mn

<2

application(s)

3D bioprinting
advanced drug delivery

greener alternative category

SMILES string

C1CCC(=O)OCC1 (Canonical-SMILES)

InChI

1S/C6H10O2/c7-6-4-2-1-3-5-8-6/h1-5H2

InChI key

PAPBSGBWRJIAAV-UHFFFAOYSA-N

General description

Polycaprolactone (PCL) is a semi crystalline hydrophobic biodegradable polyester which finds major applications as a drug delivery agent because of its cost efficiency, high toughness and biocompatibility. PCL possesses some unique properties such as:
  • It degrades slower than other biodegradable polyesters in physiological condition, this property can be exploited in the controlled release of drugs in target tissues over a period of time.
  • Its poor surface wetting and interaction with biological fluids on account of its hydrophobicity leads to poor cell adhesion and proliferation, hence it is blended with other synthetic /natural polymers.
We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

Application

  • PCL loaded with antibiotics may be used to treat infections of the respiratory tract, like tuberculosis.
  • Investigations were carried out based upon phenotypic responses of human bone marrow mesenchymal cells (hBMSCs) for different ratio of chitosan/ polycaprolactone (PCL) blends.
  • PCL/biomedical ceramic materials have been studied for possible osteo tissue regeneration.
  • Action of PCL/graded insulin/beta-5 glycerophosphate concentrations on osteochondral tissue formation through adipose-derived stromal cell differentiation.
  • Other general uses include:extrusion aid, die lubricant, mold release, pigment and filler dispersion aid and polyester segments in urethanes and block polyesters.

Features and Benefits

Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

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Tato položka
704105900820900825
description

average Mn 80,000

description

average Mn 45,000

description

viscosity 1.7 dL/g 

description

viscosity 0.40 dL/g 

form

pellets (~3 mm)

form

pellets

form

chunks

form

chunks

density

1.145 g/mL at 25 °C

density

-

density

-

density

-

mp

60 °C (lit.)

mp

56-64 °C, 60 °C (lit.)

mp

-

mp

-

impurities

<0.5% water

impurities

-

impurities

≤0.5 Residual monomer (GC), ≤0.5% Residual Water content (colormetric titration), ≤100 ppm Tin (AAS)

impurities

≤0.5% Residual Water content (colormetric titration), ≤0.5% Residual monomer (GC), ≤100 ppm Tin (AAS)

mol wt

average Mn 80,000

mol wt

Mn 40,000-50,000, Mw 48,000-90,000, average Mn 45,000

mol wt

-

mol wt

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100


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Explore all of our products under Polycaprolactone


Skladovací třída

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Osvědčení o analýze (COA)

Lot/Batch Number

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Questions

1–5 of 5 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Could you please provide the processing parameters for product 440744?

    1 answer
    1. The production process is proprietary. However, the product is a homopolymer of ε-caprolactone with a concentration of ester bond at 610 - 615 M. It has a hydroxyl end group and a melting range of 58 - 60 °C.

      Helpful?

  4. I would like to know the standard curve of UV-vis absorbance of polycaprolactone.

    1 answer
    1. This product is not tested for data for UV-Vis absorbance, but one source shows it here: https://www.researchgate.net/figure/A-UV-vis-spectra-of-polycaprolactone-PCL-and-aminolysed-PCL-samples-Right-panel_fig4_319107535

      Please note, the curve cannot be guaranteed as this is not something that is tested internally.

      Helpful?

  5. What are the processing parameters for the product?

    1 answer
    1. The production process is considered proprietary, however the following details may be shared: The product is a homopolymer of ε-caprolactone The concentration of ester bond is 610 - 615 M. The product has a hydroxyl end group. The melting range is 58 - 60 °C.

      Helpful?

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