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309567

(Methoxymethyl)triphenylphosphonium chloride

97%

Synonyma:

Triphenyl(methoxymethyl)phosphonium chloride

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Vám/Skladová položkaDostupnostCena

O této položce

Lineární vzorec:
(C6H5)3P(Cl)CH2OCH3
Číslo CAS:
Molekulová hmotnost:
342.80
UNSPSC Code:
12352107
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-664-5
Beilstein/REAXYS Number:
3599844
MDL number:
Assay:
97%
Form:
solid
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Quality Segment

assay

97%

form

solid

reaction suitability

core: phosphonium, reaction type: C-C Bond Formation

mp

185-195 °C (dec.) (lit.)

functional group

ether, phosphine

SMILES string

[Cl-].COC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1

InChI key

SJFNDMHZXCUXSA-UHFFFAOYSA-M

Application

(Methoxymethyl)triphenylphosphonium chloride is a Wittig reagent that reacts with aldehydes and ketones to give substituted alkenes. This Wittig reaction finds application as the key step in the synthesis of:
  • Antimalarial drug, (+)-artemisinin.
  • Substituted quinolines.
  • Akuammiline alkaloid picrinine.
  • 7H-pyrrolo[2,3-d]pyrimidine derivatives for signal transducers and activators of transcription 6 (STAT6) inhibitors.


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Tato položka
47718B32807766992
description

97%

description

≥97.0% (AT)

description

99%

description

97%

assay

97%

assay

≥97.0% (AT)

assay

99%

assay

97%

reaction suitability

core: phosphonium, reaction type: C-C Bond Formation

reaction suitability

core: phosphonium, reaction type: C-C Bond Formation

reaction suitability

core: phosphonium, reaction type: C-C Bond Formation

reaction suitability

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

form

solid

form

solid

form

powder

form

liquid

mp

185-195 °C (dec.) (lit.)

mp

209-212 °C (dec.) (lit.)

mp

≥300 °C (lit.)

mp

-

functional group

ether, phosphine

functional group

aldehyde, phosphine

functional group

-

functional group

fluoro, phosphonate


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pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Skladovací třída

11 - Combustible Solids

wgk

WGK 2

flash_point_f

>482.0 °F

flash_point_c

> 250 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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