171859

Methyl propiolate

99%

• Synonyma: Methyl acetylenecarboxylate
• Lineární vzorec: HC≡CCO₂CH₃
• Číslo CAS: 922-67-8
• Molekulová hmotnost: 84.07
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24850388
• EC Number: 213-083-5
• Beilstein/REAXYS Number: 605462
• MDL number: MFCD00008572
• Assay: 99%
• Form: liquid

Vlastnosti

• Quality Segment: 200
• assay: 99%
• form: liquid
• refractive index: n20/D 1.408 (lit.)
• bp: 103-105 °C (lit.)
• density: 0.945 g/mL at 25 °C (lit.)
• functional group: ester
• SMILES string: COC(=O)C#C
• InChI: 1S/C4H4O2/c1-3-4(5)6-2/h1H,2H3
• InChI key: IMAKHNTVDGLIRY-UHFFFAOYSA-N

Popis

Application

Methyl propiolate was used in the synthesis of polysubstituted 3-arylaminoacrylate and tetrahydropyrimidin-2-one derivatives. It was also used as a thiol derivatizing agent for capillary electrophoresis.

N-3 protecting reagent for uridines and thymidines.

Used in a one-pot, four-component synthesis of 1,2,3,5-benzenetetracarboxylates promoted by Ph3P.

Bezpečnostní informace

• Piktogramy: GHS02,GHS07
• Výstražné slovo: Danger
• Kódy nebezpečí: H225,H315,H319,H335
• Bezpečnostní pokyny: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Cílové orgány: Respiratory system
• Skladovací třída: 3 - Flammable liquids
• Co se děje?: WGK 3
• Bod vzplanutí (°F): 60.8 °F - closed cup
• Bod vzplanutí (°C): 16 °C - closed cup
• PPE (osobní ochranné prostředky): Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter