167398

tert-Butyl carbamate

98%

• Synonyma: Boc-amide
• Lineární vzorec: NH₂COOC(CH₃)₃
• Číslo CAS: 4248-19-5
• Molekulová hmotnost: 117.15
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24850207
• EC Number: 224-209-3
• Beilstein/REAXYS Number: 1744500
• MDL number: MFCD00007962
• Assay: 98%
• Form: solid

Vlastnosti

• Quality Segment: 200
• assay: 98%
• form: solid
• mp: 105-108 °C (lit.)
• functional group: amine
• SMILES string: CC(C)(C)OC(N)=O
• InChI: 1S/C5H11NO2/c1-5(2,3)8-4(6)7/h1-3H3,(H2,6,7)
• InChI key: LFKDJXLFVYVEFG-UHFFFAOYSA-N

Popis

General description

Palladium-catalyzed cross-coupling reaction of tert-butyl carbamate with various aryl(Het) halides with Cs₂CO₃ as base in 1,4-dioxane (solvent) has been investigated.

Application

tert-Butyl carbamate was used in palladium-catalyzed synthesis of N-Boc-protected anilines. It was used in the synthesis of tetrasubstituted pyrroles, functionalized with ester or ketone groups at C-3 position.

Bezpečnostní informace

• Skladovací třída: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)