Heptafluorobutyric anhydride is a perfluoroacylated acylation reagent, that forms stable, volatile derivatives with alcohols, amines, and phenols. It is majorly used to prepare electron-capturing derivatives for GC/electron capture detection. It is generally used with an acid scavenger, to help drive the reaction to completion and to prevent column damage from acidic by-products of the derivatization reaction. It is also used for the frequent testing of drugs of abuse such as, amphetamines and phencyclidine by GC-MS technique.
Clear borosilicate glass, high hydrolytic resistance (Type I)
Analysis Note
Suitable for derivatization of aldosterone, digoxin, digitoxin and metabolites, estradiol, postaglandins F1α and F2α, 3-oxo-Δ4-steroids, steroids and testosterone.
Other Notes
HFAA acylates amines, amino acids and other compounds. HFBA derivatives are highly volatile: used in GC separation[1][2]
Reagent for 3-enol heptafluorobutyrate, heptafluorobutyrate, heptafluorobutyryl, 17-heptafluorobutyryl and 17-heptafluorobutyrate.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
The analysis of ethyl glucuronide (EtG) in hair is a powerful tool for chronic alcohol abuse control because of the typical wide detection window of the hair matrix and due to the possibility of segmentation, allowing evaluation of alcohol consumption
In previous articles [Anal. Biochem. 284 (2000) 201; J. Lipid Res. 43 (2002) 794], we reported that the GC/MS identification and quantification of nearly all constituents of glycolipids could be obtained on the same sample in a single GC/MS analysis
Journal of analytical toxicology, 22(1), 45-49 (1998-03-10)
The use of mushrooms containing the hallucinogenic substance psilocybin for intentional intoxication is relatively common. Occasionally, this results in adverse reactions with typical tachycardia that is not evidently caused by psilocybin. This study demonstrates the presence of phenylethylamine in the
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
