07-324
Anti-PP2A Antibody, C subunit
Upstate®, from rabbit
Synonym(s):
Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C
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All Photos(2)
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
bovine, rat, human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PPP2CA(5515)
Specificity
PP2A catalytic subunit
Immunogen
peptide corresponding to amino acids 290-304 (DPAPRRGEPHVTRRT) of human PP2A
Application
Research Category
Signaling
Neuroscience
Signaling
Neuroscience
Research Sub Category
Oxidative Stress
Neurodegenerative Diseases
Oxidative Stress
Neurodegenerative Diseases
This Anti-PP2A Antibody, C subunit is validated for use in WB for the detection of PP2A.
Quality
routinely evaluated by immunoblot on RIPA lysates from mouse brain, heart, testes and spleen homogenates
Target description
36kDa
Physical form
0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30%
Immunoaffinity Chromatography
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Rongbin Hu et al.
Plant, cell & environment, 40(1), 150-164 (2016-10-28)
Protein phosphatase 2A (PP2A) is an enzyme consisting of three subunits: a scaffolding A subunit, a regulatory B subunit and a catalytic C subunit. PP2As were shown to play diverse roles in eukaryotes. In this study, the function of the
Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Sana Ando et al.
The Journal of biological chemistry, 300(5), 107277-107277 (2024-04-09)
Protein phosphatase 2A (PP2A) is an essential serine/threonine protein phosphatase, and its dysfunction is involved in the onset of cancer and neurodegenerative disorders. PP2A functions as a trimeric holoenzyme whose composition is regulated by the methyl-esterification (methylation) of the PP2A
Shunya Tsuji et al.
The Journal of veterinary medical science, 81(10), 1424-1430 (2019-09-19)
Osteosarcoma (OSA) is the most common bone tumor in dogs. Protein phosphatase 2A (PP2A), an evolutionary conserved serine/threonine protein phosphatase, is a crucial tumor suppressor. SET is a PP2A inhibitory protein that directly interacts with PP2A and suppresses its phosphatase
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