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W530066

Sigma-Aldrich

Tocopherols

mixed, Low-α type, FCC, FG

Synonym(s):

Methyltocols

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About This Item

CAS Number:
1406-66-2
UNSPSC Code:
12164502
eCl@ss:
34058016
NACRES:
NA.21

biological source

vegetable oil

Quality Level

400

grade

FG
Kosher

reg. compliance

EU Regulation 1333/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 184.1890

refractive index

n20/D 1.501

bp

>200 °C

density

0.930 g/mL at 25 °C

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

soybeans

Organoleptic

faint

InChI

1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3

InChI key

QUEDXNHFTDJVIY-UHFFFAOYSA-N

General description

Tocopherols (mixture of D-α, D-β, D-Δ, and D-γ-tocopherols) are the isomers of Vitamin E.

Application

Antioxidant used with fats and oils to delay rancidity onset

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

>392.0 °F - closed cup

Flash Point(C)

> 200 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
SHBQ0117
SHBN3969
SHBM8140
MKCJ3479
MKCB7546

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Jihyeung Ju et al.
Carcinogenesis, 31(4), 533-542 (2009-09-15)
The cancer-preventive activity of vitamin E has been studied. Whereas some epidemiological studies have suggested a protective effect of vitamin E against cancer formation, many large-scale intervention studies with alpha-tocopherol (usually large doses) have not demonstrated a cancer-preventive effect. Studies
Jonathan Himmelfarb et al.
Journal of the American Society of Nephrology : JASN, 25(3), 623-633 (2013-12-29)
Increased markers of oxidative stress and acute-phase inflammation are prevalent in patients undergoing maintenance hemodialysis therapy (MHD), and are associated with increased mortality and hospitalization rates and decreased erythropoietin responsiveness. No adequately powered studies have examined the efficacy of antioxidant
Dean DellaPenna et al.
Annual review of plant biology, 57, 711-738 (2006-05-04)
Carotenoids and tocopherols are the two most abundant groups of lipid-soluble antioxidants in chloroplasts. In addition to their many functional roles in photosynthetic organisms, these compounds are also essential components of animal diets, including humans. During the past decade, a
Benoit Blanchard et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(28), 11633-11642 (2013-07-12)
Multiple sclerosis (MS) is an inflammatory disease of the CNS that is associated with demyelination and axonal loss, resulting in severe neurological handicap. Current MS therapies mostly target neuroinflammation but have only a little impact on CNS myelin repair. Progress
William L Stone et al.
Annals of the New York Academy of Sciences, 1031, 223-233 (2005-03-09)
Colorectal cancer is the second most common cause of cancer deaths in the United States. Vitamin E (VE) and other antioxidants may help prevent colon cancer by decreasing the formation of mutagens arising from the free radical oxidation of fecal
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