858919

D-Proline

≥99%, for peptide synthesis, ReagentPlus^®

• Synonym(s): (R)-Pyrrolidine-2-carboxylic acid
• Empirical Formula (Hill Notation): C₅H₉NO₂
• CAS Number: 344-25-2
• Molecular Weight: 115.13
• Beilstein: 80811
• EC Number: 206-452-7
• MDL number: MFCD00064317
• UNSPSC Code: 12352209
• PubChem Substance ID: 24888479
• NACRES: NA.22

Properties

• product name: D-Proline, ReagentPlus^®, ≥99%
• Quality Level: 200
• product line: ReagentPlus^®
• Assay: ≥99%
• form: powder
• optical activity: [α]22/D +85.0°, c = 4 in H₂O
• optical purity: ee: 98% (GLC)
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 223 °C (dec.) (lit.)
• application(s): peptide synthesis
• SMILES string: OC(=O)[C@H]1CCCN1
• InChI: 1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
• InChI key: ONIBWKKTOPOVIA-SCSAIBSYSA-N

Description

Application

D-Proline is a key starting material in the total synthesis of (−)-secu′amamine A and (R)-harmicine.

• It can be used as a ligand for the synthesis of chiral polyoxometalate (POM) clusters.
• It can also be used as a catalyst in the enantioselective α-aminoxylation of aldehydes.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves