Recommended Products
Quality Level
Assay
96%
optical activity
[α]23/D −30°, c = 1 in H2O
mp
200-203 °C (lit.)
functional group
amine
carboxylic acid
hydroxyl
SMILES string
NCC[C@H](O)C(O)=O
InChI
1S/C4H9NO3/c5-2-1-3(6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
InChI key
IVUOMFWNDGNLBJ-VKHMYHEASA-N
Looking for similar products? Visit Product Comparison Guide
General description
(S)-(-)-4-Amino-2-hydroxybutyric acid is an important moiety of butirosin, an aminoglycoside antibiotic.
Application
(S)-(-)-4-Amino-2-hydroxybutyric acid may be used in the preparation of 6′-amino-1-N-[(S)-4-amino-2-hydroxybutyryl]-6′-deoxylividomycin A.
Building block for enantiopure 3-hydroxypyrrolidin-2-ones.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
The Journal of antibiotics, 35(11), 1507-1512 (1982-11-01)
A semisynthetic aminoglycoside antibiotic 15, containing a cyclic gamma-amino-alpha-hydroxy acid, related to the 1-N-4-amino-2-hydroxybutyric acid (AHBA) side chain of butirosins and amikacin, has been prepared. Conveniently protected 3,2',6'-tris-N-tert-butoxycarbonylgentamicin C1a (12) was condensed with the phtalimido active ester 10 to give
Synthesis of (S)-Isoserine.
Agricultural and Biological Chemistry, 40(8), 1651-1652 (1976)
Synthesis of 6'-Amino-1-N-[(S)-4-Amino-2-Hydroxybutyryl]-6'-Deoxylividomycin A.
Bulletin of the Chemical Society of Japan, 48(8), 2303-2305 (1975)
Journal of the Chemical Society. Chemical Communications, 231-231 (1995)
The Journal of antibiotics, 53(10), 1158-1167 (2001-01-02)
Butirosin is an interesting 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotic produced by non-actinomycete Bacilli. Recently we were successful in purification of 2-deoxy-scyllo-inosose synthase from butirosin-producer Bacillus circulans as the key enzyme for the biosynthesis of DOS, in cloning of the responsible gene
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service