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P8759

Sigma-Aldrich

Pyrogallol Red

Powder

Synonym(s):

Pyrogallolsulfonephthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12O8S
CAS Number:
Molecular Weight:
400.36
Beilstein:
61394
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Pyrogallol Red, Suitable for use as a complexometric indicator

Quality Level

form

powder

technique(s)

titration: suitable

color

green to very dark green, and brown

mp

≥300 °C (lit.)

solubility

1 M NH4OH: 10 mg/mL, clear

εmax

≥450 at 475 nm in methanol

suitability

suitable for complexometric indicator

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1ccc2c(Oc3c(O)c(O)ccc3C24OS(=O)(=O)c5ccccc45)c1O

InChI

1S/C19H12O8S/c20-12-7-5-10-17(15(12)22)26-18-11(6-8-13(21)16(18)23)19(10)9-3-1-2-4-14(9)28(24,25)27-19/h1-8,20-23H

InChI key

KUQNCHZOCSYKOR-UHFFFAOYSA-N

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General description

Pyrogallol red (PGR) is an ortho-diphenolic dye. It has high reactivity towards reactive oxygen species (ROS) and reactive nitrogen species (RNS) that include peroxynitrite, radical, peroxyl radicals, hypochlorite & superoxide anion.

Application

Pyrogallol Red is suitable to prepare Fujita and Watanabe dye reagent used in Pyrogallol Red-Molybdenum (IV) complex (PR) method for the determination and quantification of urinary proteins.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Juan David Figueroa et al.
Redox biology, 24, 101207-101207 (2019-05-19)
Carbonate radicals (CO3-) are generated by the bicarbonate-dependent peroxidase activity of cytosolic superoxide dismutase (Cu,Zn-SOD, SOD-1). The present work explored the use of bleaching of pyrogallol red (PGR) dye to quantify the rate of CO3- formation from bovine and human
Yo Omata et al.
Journal of agricultural and food chemistry, 56(9), 3386-3390 (2008-04-09)
The radical-scavenging antioxidants play an important role against oxidative stress in the defense system in vivo. The beneficial effects of antioxidants contained in foods and beverages have been well-accepted, and their antioxidant capacity has been assessed by various methods. In
Piyali Chatterjee et al.
PloS one, 7(7), e41884-e41884 (2012-08-01)
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal immune system activation, inflammation, and endothelial dysfunction. Toll-like receptor (TLR) 3 activation by double-stranded RNA (dsRNA) and TLR7/8 activation by single-stranded RNA (ssRNA) expressed by viruses and/or released from
Tomoko Usui et al.
Clinical and experimental nephrology, 24(2), 151-156 (2019-11-18)
Urine dipstick tests are often used to evaluate proteinuria during health checkups. We examined the dipstick's accuracy in assessing the proteinuria levels among Japanese workers. We assessed subjects aged ≥ 18 years who had a health checkup at the University of Tokyo in
Randolph B Caldwell et al.
Applied and environmental microbiology, 70(1), 610-612 (2004-01-09)
A simple and reliable method for precipitating protein from bacterial culture supernatants based on a pyrogallol red-molybdate-methanol (PRMM) protocol has been developed and applied for the analysis of proteins secreted by a bacterial type III secretion system. PRMM-based precipitation has

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