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Sigma-Aldrich

Poly(ethylene glycol) dithiol

average Mn 1, 500, thiol

Synonym(s):

Polyethylene glycol, PEG dithiol

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About This Item

Linear Formula:
HSCH2CH2(OCH2CH2)nSH
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) dithiol, average Mn 1,500

form

solid

Quality Level

100

mol wt

Mn 1200-1800
average Mn 1,500

reaction suitability

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

47-50 °C

Ω-end

thiol

α-end

thiol

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

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Application

  • Photocurable Bioink for the Inkjet 3D Pharming of Hydrophilic Drugs.: This research discusses the development of a photocurable bioink using poly(ethylene glycol) dithiol for the inkjet 3D printing of hydrophilic drugs. The study highlights the biocompatibility and potential applications in drug delivery systems (Acosta-Vélez et al., 2017).
  • Enhanced mechanical properties of photo-clickable thiol-ene PEG hydrogels through repeated photopolymerization of in-swollen macromer.: This study examines the use of poly(ethylene glycol) dithiol in creating thiol-ene hydrogels with enhanced mechanical properties. The repeated photopolymerization technique improves the hydrogel′s stability and applicability in medical devices and tissue engineering (Fiedler et al., 2016).
  • Degradative properties and cytocompatibility of a mixed-mode hydrogel containing oligo[poly(ethylene glycol)fumarate] and poly(ethylene glycol)dithiol.: The paper explores the degradative behavior and cytocompatibility of hydrogels composed of oligo[poly(ethylene glycol)fumarate] and poly(ethylene glycol)dithiol. The findings indicate favorable biocompatibility and potential for biomedical applications such as drug delivery and tissue engineering (Brink et al., 2009).

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

>230.0 °F

Flash Point(C)

> 110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Kelly C Santos Roballo et al.
Biomaterials, 209, 1-9 (2019-04-26)
Segmental injuries to peripheral nerves (PNs) too often result in lifelong disability or pain syndromes due to a lack of restorative treatment options. For injuries beyond a critical size, a bridging device must be inserted to direct regeneration. PN allografts

Articles

Poly(ethylene glycol) (PEG) and Synthetic PEG Derivatives for Tissue Engineering and Cell Delivery

Highlighting new synthetic modifications of PEG to improve the mechanical properties and degradation of resulting hydrogels in tissue engineering applications.

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