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1589007

USP

Pyrimethamine

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine

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About This Item

Fórmula empírica (notación de Hill):
C12H13ClN4
Número de CAS:
58-14-0
Peso molecular:
248.71
Beilstein/REAXYS Number:
219864
MDL number:
MFCD00057350
UNSPSC Code:
41116107
PubChem Substance ID:
329750999
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

pyrimethamine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCC1=NC(N)=NC(N)=C1C2=CC=C(Cl)C=C2

InChI

1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)

InChI key

WKSAUQYGYAYLPV-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pyrimethamine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Pyrimethamine Tablets
  • Sulfadoxine and Pyrimethamine Tablets
  • Pyrimethamine Compounded Oral Suspension

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Malaria journal, 13, 358-358 (2014-09-14)
In sub-Saharan Africa, artemisinin-based combination therapy (ACT) and injectable artesunate are the first-line treatments for uncomplicated and severe Plasmodium falciparum malaria, respectively. However, recent studies suggest that delayed anaemia is associated with these treatments in non-immune travellers. This paper aimed
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Phytochemistry, 105, 52-59 (2014-07-21)
The stem bark of Polyalthia oliveri was screened for its chemical constituents using liquid chromatography high resolution mass spectrometry resulting in the isolation of three indolosesquiterpene alkaloids named 8α-polyveolinone (1), N-acetyl-8α-polyveolinone (2) and N-acetyl-polyveoline (3), together with three known compounds
Abdoulaye Gaye et al.
The American journal of tropical medicine and hygiene, 92(3), 648-652 (2015-01-28)
Direct skin feeding experiments are sensitive assays to determine human infectiousness to mosquitoes but are rarely used in malaria epidemiological surveys. We determined the infectiousness of inhabitants of a malaria hypoendemic area in Senegal. Gametocyte prevalence by microscopy was 13.5%
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Drug metabolism and pharmacokinetics, 29(3), 266-271 (2014-01-07)
Telaprevir-based triple therapy is a highly effective treatment for chronic hepatitis C. However, adverse reactions include reversible and dose-dependent elevation of serum creatinine levels. We speculated that this effect reflects inhibition of the renal organic cation transporters hOCT2, hMATE1, and
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Parasitology research, 114(2), 631-639 (2014-12-06)
The invasive and motile life stages of malaria parasites (merozoite, ookinete and sporozoite) possess a distinctive cortical structure termed the pellicle. The pellicle is characterised by a double-layered 'inner membrane complex' (IMC) located underneath the plasma membrane, which is supported
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