59140-U
SUPELCOSIL™ LC-ABZ (5 µm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Sinónimos:
Amino-Benzene-Zone HPLC Column
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About This Item
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Nombre del producto
Columna de HPLC SUPELCOSIL™ LC-ABZ, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
Materiales
stainless steel column
Nivel de calidad
Agency
suitable for USP L60
Línea del producto
SUPELCOSIL™
Características
endcapped
fabricante / nombre comercial
SUPELCOSIL™
envase
1 ea of
Extensión del etiquetado
12.0% carbon loading
Parámetros
≤70 °C temp. limit
400 bar pressure (5801 psi)
técnicas
HPLC: suitable
L × D.I.
15 cm × 4.6 mm
superficie
170 m2/g
cobertura de la superficie
surface coverage 3.4 μmol/m2
Matriz
silica gel, spherical particle platform
fully porous particle
grupo activo de la matriz
amide, alkyl phase
tamaño de partícula
5 μm
tamaño de poro
120 Å
intervalo de pH
2-7.5
aplicaciones
food and beverages
técnica de separación
reversed phase
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Descripción general
SUPELCOSIL LC-ABZ phase has a unique deactivation technology which provides excellent reversed phase performance for basic compounds, as well as those that are acidic, polar neutral, and non-polar. Silanol suppressing additives and techniques such as competing amines, high ionic strength, and pH extremes are typically not required to obtain good peak shape on the LC-ABZ phase.
Aplicación
- Validation of a high-performance liquid chromatography method for the assay of and determination of related organic impurities in nevirapine drug substance.: This paper validates a method using the SUPELCOSIL™ LC-ABZ HPLC Column for assessing purity and impurities in HIV medication, showcasing the column′s high specificity and reproducibility (Li et al., 2000).
- A comparative study of the reversed-phase HPLC retention behaviour of S-adenosyl-L-methionine and its related metabolites on Hypersil ODS and Supelcosil LC-ABZ stationary phases.: This comparative study provides insights into the retention behaviors of bioactive compounds on SUPELCOSIL™ LC-ABZ, affirming its versatility and robust performance in complex biochemical separations (Valkó et al., 1993).
Características y beneficios
• For acids, bases, zwitterions
• Increased polar retention relative to standard reversed-phases
• Unique selectivity
• Silanol deactivation
• Peak shape, efficiency, and retention are comparable to C8 phases for non-polar analytes
• Increased polar retention relative to standard reversed-phases
• Unique selectivity
• Silanol deactivation
• Peak shape, efficiency, and retention are comparable to C8 phases for non-polar analytes
Información legal
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Aplicación
Referencia del producto
Descripción
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Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Murali Pendela et al.
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
D Korakas et al.
Journal of pharmaceutical and biomedical analysis, 12(9), 1141-1145 (1994-09-01)
A series of biologically active peptides and their conjugates with lipidic amino acids were investigated by systematic change of the mobile phase composition using traditional octadecylsilica stationary phase and the newly developed Supelcosil LC-ABZ column. The mobile phases contained various
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
K Valkó et al.
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
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