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T0625

Sigma-Aldrich

Taurine

≥99%

Sinónimos:

2-Aminoethanesulfonic acid

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About This Item

Fórmula lineal:
NH2CH2CH2SO3H
Número de CAS:
107-35-7
Peso molecular:
125.15
Beilstein:
1751215
Número CE:
203-483-8
Número MDL:
MFCD00008197
Código UNSPSC:
12352106
ID de la sustancia en PubChem:
24278721
NACRES:
NA.32

Nombre del producto

Taurine, ≥99%

origen biológico

synthetic

Nivel de calidad

200

Ensayo

≥99%

Formulario

powder

color

white

mp

>300 °C (lit.)

aplicaciones

cell analysis

temp. de almacenamiento

room temp

cadena SMILES

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

Clave InChI

XOAAWQZATWQOTB-UHFFFAOYSA-N

Información sobre el gen

human ... GRIN1(2902)
rat ... Ppm1a(24666)

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Descripción general

Taurine (2-aminoethanesulphonic acid) is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys.

Aplicación

Taurine has been used for the isolation and growth of taurine-utilizing purple non-sulfur bacteria and in phototrophic growth experiments.

Acciones bioquímicas o fisiológicas

Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine modulates the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. It also has a role in bile formation and fat digestion. Deficiency of taurine is associated with anxiety, hyperactivity, epilepsy and depression.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCM1314
BCCM5726
BCCK5785
BCCC3480
BCCJ3267

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Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides.
Novak RT
Microbiology, 150(Pt 6), 1881-1891 (2004)
The potential health benefits of taurine in cardiovascular disease.
Xu YJ
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
Shozo Sonoda et al.
Nature protocols, 4(5), 662-673 (2009-04-18)
We provide our detailed, standardized in vitro protocol for the culture and differentiation of human retinal pigment epithelial (RPE) cells into a highly polarized and functional monolayer. Disruption of the polarized RPE function plays an important role in the pathogenesis
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as
Deniz Tasdemir et al.
Bioorganic & medicinal chemistry, 15(21), 6834-6845 (2007-09-04)
The type II fatty acid pathway (FAS-II) is a validated target for antimicrobial drug discovery. An activity-guided isolation procedure based on Plasmodium falciparum enoyl-ACP reductase (PfFabI) enzyme inhibition assay on the n-hexane-, the CHCl(3-) and the aq MeOH extracts of
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