SRP0300
TGF-β1 Latent human
recombinant, expressed in FreeStyle™ 293-F cells, ≥98% (SDS-PAGE)
Sinónimos:
LAP, TGFb1, TGFbeta1, latency-associated peptide, transforming growth factor beta-1
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About This Item
Código UNSPSC:
12352202
NACRES:
NA.32
Productos recomendados
origen biológico
human
recombinante
expressed in FreeStyle™ 293-F cells
Ensayo
≥98% (SDS-PAGE)
Formulario
aqueous solution
mol peso
25 kDa
envase
pkg of 5 μg
fabricante / nombre comercial
Invitrogen
condiciones de almacenamiento
avoid repeated freeze/thaw cycles
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
dry ice
temp. de almacenamiento
−70°C
Información sobre el gen
human ... LTBP1(4052)
Descripción general
Human TGFβ1 (GenBank Accession No. NM_000660), amino acids 30-390 (end) with Cys33Ser mutation and N-terminal His-tag, disulfide-linked homodimers of TGFβ1 LAP and mature TGFβ1, MW= ~75kDa and 25kDa, under non-reducing conditions.
LTBP1 (latent transforming growth factor β binding protein 1) belongs to the LTBP family of proteins. The protein has 18 epidermal growth factor (EGF)-like repeats and four LTBP-like repeats. The gene is mapped to human chromosome 2p22.3.
LTBP1 (latent transforming growth factor β binding protein 1) belongs to the LTBP family of proteins. The protein has 18 epidermal growth factor (EGF)-like repeats and four LTBP-like repeats. The gene is mapped to human chromosome 2p22.3.
Aplicación
Useful for cell culture and for the study of signaling and apoptotic pathways.
Acciones bioquímicas o fisiológicas
LTBP1 (latent transforming growth factor β binding protein 1) is an extracellular matrix protein which also controls TGF-β (transforming growth factor β) bioavailability. LTBP1 is mainly responsible for the folding and secretion of TGF-β, thereby adding it to the extracellular matrix. It is a target of HTRA1 (high temperature requirement protein A1), a serine protease involved in cellular signaling.
Forma física
Lyophilized from a 0.2 μM filtered, aqueous solution.
Reconstitución
Reconstitute in sterile PBS with 0.1% BSA. Stability: >6 months at –70°C (as a solid). Store reconstituted protein in aliquots at –80°C for up to 3 months. Avoid freeze/thaw cycles.
Información legal
FreeStyle is a trademark of Invitrogen Corp.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Certificados de análisis (COA)
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