SML1646

ZQ-16

≥98% (HPLC)

• Sinónimos: 2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone
• Fórmula empírica (notación de Hill): C₁₀H₁₆N₂O₂S
• Número de CAS: 376616-73-8
• Peso molecular: 228.31
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825987
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: room temp
• SMILES string: CCCCCCSC1=NC(O)=CC(O)=N1
• InChI: 1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14)
• InChI key: UYXOAKRMLQKLQX-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

ZQ-16 is a potent and selective agonist for medium-chain free fatty acid receptor GPR84 (G protein-coupled receptor 84). ZQ-16 activates GPR84-mediated calcium mobilization, inhibition of cAMP accumulation, phosphorylation of ERK1/2, receptor desensitization and internalization, and receptor-β-arrestin interaction.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable