SML1087

Sumanirole maleate

≥98% (HPLC)

• Sinónimos: (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, CID 9818479 maleate, PNU-95,666 maleate
• Fórmula empírica (notación de Hill): C₁₁H₁₃N₃O · C₄H₄O₄
• Número de CAS: 179386-44-8
• Peso molecular: 319.31
• Número MDL: MFCD09832637
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329825464
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (HPLC)
• Formulario: powder
• actividad óptica: [α]/D -22 to -32°, c = 1 in H₂O
• condiciones de almacenamiento: desiccated
• color: white to beige
• solubilidad: H₂O: 10 mg/mL, clear
• temp. de almacenamiento: −20°C
• cadena SMILES: O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=C\C(O)=O
• InChI: 1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1
• Clave InChI: VOJRMYBBPKNLLI-ORHWHDKWSA-N

Descripción

Aplicación

Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats.

Acciones bioquímicas o fisiológicas

Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.

Sumanirole is a highly selective and potent dopamine D2 receptor agonist.

Características y beneficios

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Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable