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S9512

Sigma-Aldrich

Ácido succínico

greener alternative

BioReagent, BioRenewable, suitable for cell culture, suitable for insect cell culture

Sinónimos:

Ácido butanodióico

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About This Item

Fórmula lineal:
HOOCCH2CH2COOH
Número de CAS:
110-15-6
Peso molecular:
118.09
Beilstein/REAXYS Number:
1754069
EC Number:
203-740-4
MDL number:
MFCD00002789
UNSPSC Code:
12352207
PubChem Substance ID:
24899842
NACRES:
NA.71

Quality Level

200

product line

BioReagent

assay

≥99.0% ( with NaOH, titration)

form

powder

greener alternative product characteristics

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

density

1.564 g/cm3 at 15 °C

greener alternative category

Aligned,

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Use as a TCA (Krebs cycle) supplement in insect cell culture applications.

Other Notes

Succinic Acid: A New Platform Chemical for Biobased Polymers from Renewable Resources

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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L-(−)-Malic acid suitable for cell culture, BioReagent, suitable for insect cell culture

Sigma-Aldrich

M7397

L-(−)-Malic acid

Ácido succínico crystalline, EMPROVE® ESSENTIAL, ChP, NF, JPE, ACS

SAFC

1.00681

Ácido succínico

Sodium succinate dibasic hexahydrate ReagentPlus®, ≥99%

Sigma-Aldrich

S2378

Sodium succinate dibasic hexahydrate

Ácido succínico United States Pharmacopeia (USP) Reference Standard

USP

1623411

Ácido succínico

Muhammad Fariz Ali et al.
Pathogens (Basel, Switzerland), 9(9) (2020-09-10)
To gain insight into how pathogens adapt to new hosts, Cryptococcus neoformans (H99W) was serially passaged in Galleria mellonella. The phenotypic characteristics of the passaged strain (P15) and H99W were evaluated. P15 grew faster in hemolymph than H99W, in vitro
Corey Osto et al.
Current protocols in cell biology, 89(1), e116-e116 (2020-12-16)
Measuring oxygen consumption allows for the role of mitochondrial function in biological phenomena and mitochondrial diseases to be determined. Although respirometry has become a common approach in disease research, current methods are limited by the necessity to process and measure
Monika Bambouskova et al.
Cell reports, 34(10), 108756-108756 (2021-03-11)
Itaconate is a unique regulatory metabolite that is induced upon Toll-like receptor (TLR) stimulation in myeloid cells. Here, we demonstrate major inflammatory tolerance and cell death phenotypes associated with itaconate production in activated macrophages. We show that endogenous itaconate is
José Manuel Otero et al.
PloS one, 8(1), e54144-e54144 (2013-01-26)
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after
G M Tannahill et al.
Nature, 496(7444), 238-242 (2013-03-29)
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map
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