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RAB0705

Sigma-Aldrich

Human LTF / Lactotransferrin ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.96 ng/mL
standard curve range: 1.966-480 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LTF(4057)

General description

LTF (lactotransferrin) codes for a 80 kDa glycoprotein which is expressed in many tissues and organs such as mammary gland, uterus, kidney and brain and found in body fluids including tears, milk, vitreous humor and saliva. Lactotransferrin is considered pleiotropic. Lactotransferrin belongs to the transferrin family and is homologous in sequence and structure with iron binding protein. The LTF gene is mapped to human chromosome 3p21.31.
The LTF ELISA kit provides for the Quantitative measurement of Lactotransferrin in Cell Culture Supernatants, Plasma and Serum.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Lactotransferrin regulates the immune and inflammatory responses. Lactotransferrin is also known to be involved in bone metabolism. It might play an important role in dental osseointegration implantation. Lactotransferrin is known for its antimicrobial anti-viral, anti-fungal, anti-parasitic, anti-inflammatory and antioxidant activity. Anti-angiogenic, anti-tumor effects of this protein proves that it is a tumor suppressor. Neuronal differentiation is also an important function of lactotransferrin.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Taro Fukushi et al.
Scientific reports, 10(1), 21747-21747 (2020-12-12)
Biocompatibility of hemodialysis (HD) systems have been considerably improved. However, mortality and morbidity rates of patients have remained high, raising questions regarding the biocompatibility of current systems. In the present study, 70 patients on regular HD (51 males; mean age
Clare Dix et al.
Nutrients, 10(8) (2018-08-22)
Bovine lactoferrin, extracted from milk or whey, is used in a range of products to enhance immunity and support digestive health, iron absorption, and homeostasis. This study examined the absorption and effect of Progel (Brisbane, Queensland, Australia) microencapsulated bovine lactoferrin
Lactoferrin expression in human and murine ocular tissue.
Rageh A A, et al.
Current Eye Research, 41(7), 883-889 (2016)
Maria C Edman et al.
Scientific reports, 8(1), 11044-11044 (2018-07-25)
Cathepsin S (CTSS) activity is elevated in Sjögren's Syndrome (SS) patient tears. Here we tested whether protease inhibition and cystatin C (Cys C) levels are reduced in SS tears, which could lead to enhanced CTSS-driven degradation of tear proteins. CTSS
S Lanctôt et al.
Journal of dairy science, 100(3), 2269-2281 (2017-01-23)
The transition from lactation to the dry period in dairy cows is a period of high risk for acquiring new intramammary infections. This risk is reduced when the involution of the mammary gland is completed. Accordingly, approaches that speed up
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