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Merck

R3030

Sigma-Aldrich

Risperidone

≥98% (HPLC), powder, antipsychotic

Sinónimos:

R 64,766

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About This Item

Fórmula empírica (notación de Hill):
C23H27FN4O2
Número de CAS:
Peso molecular:
410.48
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

product name

Risperidone, ≥98% (HPLC), powder

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥5 mg/mL

originator

Johnson & Johnson

storage temp.

room temp

SMILES string

CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1

InChI

1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

InChI key

RAPZEAPATHNIPO-UHFFFAOYSA-N

Gene Information

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General description

Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D2, histamine H1 and α1 and α2 adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autism.

Application

Risperidone has been used:
  • to study its effects on bone formation and differentiation
  • to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients
  • to reverse induced schizophrenia-like behavior in mice

Biochem/physiol Actions

Risperidone is an antipsychotic; serotonin-dopamine antagonist.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Overexpression of transmembrane protein 168 in the mouse nucleus accumbens induces anxiety and sensorimotor gating deficit
Fu K, et al.
PLoS ONE, 12(12), e0189006-e0189006 (2017)
Schizophrenia (2006)
Development and validation of liquid chromatography/tandem mass spectrometry analysis for therapeutic drug monitoring of risperidone and 9-hydroxyrisperidone in pediatric patients with autism spectrum disorders
Vanwong N, et al.
Journal of Clinical Laboratory Analysis, 30(6), 1236-1246 (2016)
Effect of risperidone on proliferation and apoptosis of MC3T3-E1 cells
Zheng L, et al.
Brazilian journal of medical and biological research, 52(3) (2019)
Kaplan & Sadock's Concise Textbook of Clinical Psychiatry (2008)

Artículos

We offer many products related to dopamine receptors for your research needs.

We offer many products related to dopamine receptors for your research needs.

We offer many products related to dopamine receptors for your research needs.

We offer many products related to dopamine receptors for your research needs.

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