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Key Documents

P3150

Sigma-Aldrich

Poly(Lys, Phe) 1:1 hydrobromide

mol wt 20,000-50,000

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About This Item

Número de CAS:
26700-39-0
MDL number:
MFCD00166387
UNSPSC Code:
12352209
NACRES:
NA.26

form

powder

Quality Level

200

feed ratio

Lys:Phe (1:1)

mol wt

20,000-50,000

color

white to off-white

application(s)

cell analysis

storage temp.

−20°C

Application

Poly (Lys, Phe) 1:1 hydrobromide has been used as a surfactant to bind negatively charged plasmid DNA. It has also been used to study its interaction with solvatochromic fluorescent dyes.

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation
Emma V. Yates
The Journal of Physical Chemistry, 120 (9), 2087?2094-2087?2094 (2016)
Synthesis and properties of alternating poly(Lys-Phe) and comparison with the random copolymer poly(Lys 51, Phe 49).
G Seipke et al.
Biopolymers, 13(8), 1621-1633 (1974-01-01)
Tae Woo Kim et al.
International journal of pharmaceutics, 295(1-2), 35-45 (2005-04-26)
To enhance the in vitro and in vivo transfection activity of the cationic lipid emulsion (LE), three natural polycations, protamine sulfate (PS), poly-L-lysine and spermine, were selected as DNA condensing active agents. Formation of the LE/polycation/DNA ternary complexes was identified
Optimising DNA binding to carbon nanotubes by non-covalent methods
Vanesa Sanz
Carbon, 49(5), 1775-1781 (2011)
Helen Sjögren et al.
Biophysical chemistry, 116(1), 11-21 (2005-05-25)
The transition from alpha-helix to random coil of the titrating polyamino acid co-poly-L-(lysine, phenylalanine), (p-(Lys,Phe)), has been investigated as a function of pH and ionic strength in aqueous solution and at the air-water interface by means of circular dichroism (CD)

Artículos

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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