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O5250

Sigma-Aldrich

D-Ornithine monohydrochloride

~98%

Sinónimos:

(R)-2,5-Diaminopentanoic acid monohydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C5H12N2O2 · HCl
Número de CAS:
16682-12-5
Peso molecular:
168.62
Beilstein/REAXYS Number:
4153339
EC Number:
240-729-3
MDL number:
MFCD00012917
UNSPSC Code:
12352209
PubChem Substance ID:
24898012
NACRES:
NA.26

product name

D-Ornithine monohydrochloride, ~98%

assay

~98%

Quality Level

100

form

powder

color

white

mp

239 °C

SMILES string

Cl[H].NCCC[C@@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m1./s1

InChI key

GGTYBZJRPHEQDG-PGMHMLKASA-N

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Categorías relacionadas

Biochem/physiol Actions

D-Ornithine cleave proteins at cysteine residues.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Susan E Cellitti et al.
Nature chemical biology, 7(8), 528-530 (2011-04-29)
D-ornithine has previously been suggested to enhance the expression of pyrrolysine-containing proteins. We unexpectedly discovered that uptake of D-ornithine results in the insertion of a new amino acid, pyrroline-carboxy-lysine (Pcl) instead of the anticipated pyrrolysine (Pyl). Our feeding and biochemical
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
Isabel Araque et al.
Food microbiology, 33(1), 107-113 (2012-11-06)
The accumulation of citrulline and ornithine in wine or beer as a result of the arginine catabolism of some lactic acid bacteria (LAB) species increases the risk of ethyl carbamate and putrescine formation, respectively. Several LAB species, which are found
Manami Oya et al.
The Journal of biological chemistry, 288(7), 4513-4521 (2012-12-28)
Although amino acids are dietary nutrients that evoke the secretion of glucagon-like peptide 1 (GLP-1) from intestinal L cells, the precise molecular mechanism(s) by which amino acids regulate GLP-1 secretion from intestinal L cells remains unknown. Here, we show that
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
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