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Merck

M6546

Sigma-Aldrich

(±)-2-(p-Methoxyphenoxy)propionic acid

solid, ≥98%

Sinónimos:

PMP

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About This Item

Fórmula empírica (notación de Hill):
C10H12O4
Número de CAS:
Peso molecular:
196.20
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

product name

(±)-2-(p-Methoxyphenoxy)propionic acid, ≥98%

biological source

synthetic (organic)

Quality Level

assay

≥98%

form

solid

SMILES string

COc1ccc(OC(C)C(O)=O)cc1

InChI

1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

InChI key

MIEKOFWWHVOKQX-UHFFFAOYSA-N

Application

(±)-2-(p-Methoxyphenoxy)propionic acid may be used as a sweet taste receptor antagonist to study its effect on allulose-induced glucagon-like peptide 1 (GLP-1) secretion rats. It may also be used to study the response of the secretin tumor cell line (STC-1) to sweetener in the presence and absence of (±)-2-(p-methoxyphenoxy)propionic acid or lactisole.

Biochem/physiol Actions

As a taste modulator, the sodium salt inhibits the perception of sweetness in humans, but not in rats.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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The biological functions of cell membranes strongly influence the binding and transport of molecular species. We developed STC-1 cell line stably expressing the sweet taste receptor (T1R2/T1R3), and explored the possible correlation between sweeteners and membrane dipole potential of STC-1
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