M5793

3-Morpholinosydnonimine hydrochloride

(consistent with structure, NMR)

• Sinónimos: 3-(4-Morpholinyl)sydnone imine hydrochloride, Linsidomine hydrochloride, SIN-1 hydrochloride
• Fórmula empírica (notación de Hill): C₆H₁₀N₄O₂ · HCl
• Número de CAS: 16142-27-1
• Peso molecular: 206.63
• Número MDL: MFCD00214332
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24897048
• NACRES: NA.77

Propiedades

• Nivel de calidad: 200
• temp. de almacenamiento: −20°C
• cadena SMILES: Cl[H].[NH-]c1c[n+](no1)N2CCOCC2
• InChI: 1S/C6H10N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5,7H,1-4H2;1H
• Clave InChI: NCGICGYLBXGBGN-UHFFFAOYSA-N

Descripción

Aplicación

3-Morpholinosydnonimine hydrochloride has been used:

• as a peroxynitrite donor standard to study the accumulation of peroxynitrite in Arabidopsis thaliana
• to study its effects on nitrosative stress in human brain vascular pericytes and human embryonic kidney cells
• as a ROS to study its effects on mouse embryonic fibroblasts

Acciones bioquímicas o fisiológicas

3-Morpholinosydnonimine participates in the inhibition of cysteine proteases.

Liberates nitric oxide (NO) spontaneously when in solution, activating guanylyl cyclase and causing an increase in cyclic-GMP. This product is a vasodilator and inhibits platelet aggregation. Using molecular oxygen, it generates both superoxide anion and nitric oxide that spontaneously form peroxynitrite.

Liberates nitric oxide (NO) spontaneously when in solution, activating guanylyl cyclase and causing an increase in cyclic-GMP; vasodilator.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)